Mac and Cheese Meatloaf Casserole
After seeing this recipe, you may never make mac and cheese—or meatloaf—the same way again! This Mac and Cheese Meatloaf Casserole is the ultimate comfort food combination. It pairs a savory, BBQ-glazed meatloaf base with a creamy, cheesy layer of macaroni and a golden, bubbling top. It’s hearty, family-friendly, and perfect for cozy dinners that bring everyone to the table.
Ingredients
For the Meatloaf Layer
- Ketchup – 1 cup
- Barbecue sauce (sweet and smoky preferred) – 1 cup
- Lean ground beef – 2 lbs
- Ritz crackers, crushed – 30
- Dry onion soup mix – 2 oz
- Eggs – 2
- Salt – 1 tsp
- Black pepper – 1 tsp
- Garlic powder – 1 tbsp
- Onion powder – 1 tbsp
For the Mac and Cheese Layer
- Milk – 2 cups
- Condensed cheddar cheese soup – 10.5 oz
- Macaroni noodles – 3 cups
- Seasonings (salt, pepper, garlic powder, onion powder) – To taste
For the Topping
- Remaining ketchup and barbecue sauce mixture – ½ cup
- Shredded mozzarella and cheddar cheese blend – 4 cups (2 cups for mixing, 2 cups for topping)
Instructions
Step 1: Preheat & Prepare
Preheat your oven to 350°F (175°C). Grease a 9×13-inch baking dish with nonstick spray.
Step 2: Make the Sweet & Tangy Sauce
In a medium bowl, whisk together ketchup and barbecue sauce until smooth. Reserve ½ cup for glazing later.
Step 3: Mix the Meatloaf
In a large bowl, combine ground beef, crushed crackers, onion soup mix, eggs, ½ cup of the ketchup-barbecue mixture, salt, pepper, garlic powder, and onion powder. Mix gently until just combined—avoid overmixing to keep it tender.
Step 4: Form & Glaze the Meatloaf Layer
Press the meat mixture evenly into the prepared baking dish. Spread the remaining ½ cup of sauce evenly on top.
Step 5: Bake the Meatloaf
Bake for 30 minutes until partially cooked and the top begins to set.
Step 6: Cook the Macaroni
Meanwhile, cook the macaroni noodles according to package directions. Drain well and set aside.
Step 7: Make the Cheesy Mac & Cheese Mixture
In a large bowl, whisk together milk and condensed cheddar cheese soup until smooth. Stir in the cooked noodles, 2 cups of shredded cheese blend, and season to taste.
Step 8: Assemble the Casserole
After the meatloaf layer has baked, carefully spoon the mac and cheese mixture over the top. Spread evenly to cover the surface.
Step 9: Add Cheese & Finish Baking
Sprinkle the remaining 2 cups of shredded cheese evenly over the top. Return to the oven and bake for 17–20 minutes, or until the cheese is melted, bubbly, and lightly golden.
Step 10: Rest & Serve
Allow the casserole to cool for about 10 minutes before slicing. Serve warm and enjoy the perfect balance of savory meatloaf and creamy mac and cheese.
Chef’s Tips
- Choose the Right Cheese: A blend of sharp cheddar and mozzarella melts beautifully and adds depth of flavor.
- Add a Touch of Heat: Mix in a pinch of smoked paprika or chili flakes for a mild kick.
- Make Ahead: Assemble the casserole up to a day ahead, refrigerate, and bake just before serving.
- Storage: Store leftovers in an airtight container in the fridge for up to 3 days. Reheat in the oven for best texture.
Before you go
This Mac and Cheese Meatloaf Casserole is the kind of meal that turns an ordinary evening into a comforting family dinner. Every bite delivers creamy, cheesy goodness layered over hearty, smoky meatloaf—proof that two comfort food classics really are better together!
